Diabetes in Mice Galectin-1 Delay Onset of Autoimmune Dendritic Cells Expressing Transgenic
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منابع مشابه
Dendritic cells expressing transgenic galectin-1 delay onset of autoimmune diabetes in mice.
Type 1 diabetes (T1D) is a disease caused by the destruction of the beta cells of the pancreas by activated T cells. Dendritic cells (DC) are the APC that initiate the T cell response that triggers T1D. However, DC also participate in T cell tolerance, and genetic engineering of DC to modulate T cell immunity is an area of active research. Galectin-1 (gal-1) is an endogenous lectin with regulat...
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تاریخ انتشار 2006